《中国神经再生研究（英文版）》最新发布文章

2023年第12期

NEURAL REGENERATION RESEARCH

Vol 18｜No. 12｜December 2023

综述

Cytokines, synaptic plasticity and network dynamics: a matter of balance

细胞因子、突触可塑性和网络动力学：平衡问题

Laura Bellingacci, Jacopo Canonichesi, Andrea Mancini, Lucilla Parnetti, Massimiliano Di Filippo

Molecular chaperones in stroke-induced immunosuppression

脑卒中诱导免疫抑制中的分子伴侣

Haoduo Qiao, Qing Xu, Yunfei Xu, Yao Zhao, Nina He, Jie Tang, Jie Zhao, Ying Liu

The importance of laminin at the bloodbrain barrier

层粘连蛋白在血脑屏障中的重要性

Sebok K. Halder, Arjun Sapkota, Richard Milner

Axonal growth inhibitors and their receptors in spinal cord injury: from biology to clinical translation

展开全文

脊髓损伤中的轴突生长抑制剂及其受体：从生物学到临床转化

Sílvia Sousa Chambel, Célia Duarte Cruz

Therapies for Tau-associated neurodegenerative disorders: targeting molecules, synapses, and cells

Tau相关神经退行性疾病的治疗：靶向分子、突触和细胞

Miranda A. Robbins

Thinking outside the black box: are the brain endothelial cells the new main target in Alzheimer’s disease?

黑匣子之外的思考：脑内皮细胞是阿尔茨海默病的新主要靶点吗？

Enrique Estudillo, Adolfo López-Ornelas, Alejandro Rodríguez-Oviedo, Neptali Gutiérrez de la Cruz, Marco Antonio Vargas-Hernández, Adriana Jiménez

Saliva: a challenging human fluid to diagnose brain disorders with a focus on Alzheimer’s disease

唾液：诊断大脑疾病的一种具有挑战性的人体液体，重点是阿尔茨海默病

Christine Zürcher, Christian Humpel

The role of natural flavonoids on neuroinflammation as a therapeutic target for Alzheimer’s disease: a narrative review

天然黄酮类化合物靶向干预阿尔茨海默病的神经炎症

Qian Zhang, Yaping Yan

Gut-microbiome-brain-axis: the crosstalk between the vagus nerve, alpha-synuclein and the brain in Parkinson’s disease

肠道-微生物组-脑轴：帕金森病中迷走神经、α-突触核蛋白和大脑之间的串扰

Júlio César Claudino dos Santos, Leandro Freitas Oliveira, Felipe Micelli Noleto, Camilla Teixeira Pinheiro Gusmão, Gerly Anne de Castro Brito, Glauce Socorro de Barros Viana

CDP-choline to promote remyelination in multiple sclerosis: the need for a clinical trial

CDP胆碱促进多发性硬化髓鞘再形成：临床试验的必要性

Viktoria Gudi, Paweł Grieb, Ralf A. Linker, Thomas Skripuletz

Repair and regeneration of peripheral nerve injuries that ablate branch points

切断分支点的周围神经损伤的修复与再生

JuliAnne E. Allgood, George D. Bittner, Jared S. Bushman

Animal models of vascularized nerve grafts: a systematic review

血管化神经移植的动物模型：系统综述

Francesca Toia, Daniele Matta, Federico De Michele, Roberto Pirrello, Adriana Cordova

Retinoprotective compounds, current efficacy, and future prospective

视网膜保护化合物、当前疗效和未来前景

Rachele Marino, Rebecca Sappington, Marco Feligioni

Potential Role of Lycium barbarum polysaccharides in glaucoma management: evidence from preclinical in vivo studies

枸杞多糖在青光眼治疗中的潜在作用：临床前体内研究的证据

Yamunadevi Lakshmanan, Francisca Siu Yin Wong, Kwok-Fai So, Henry Ho-Lung Chan

观点

GABAergic synaptic transmission and plasticity oscillate across sleep and wake

GABA能突触传递和可塑性在睡眠和觉醒中振荡

Kunwei Wu, Wei Lu

Role of exercise in the brain: focus on oligodendrocytes and remyelination

运动在大脑中的作用：关注少突胶质细胞和髓鞘再形成

Grazia Maugeri, Velia D’Agata, Giuseppe Musumeci

Focus on LPA signaling: A promising therapeutic target to foster regeneration in immune-mediated neuropathies

关注LPA信号传导：促进免疫介导的神经病再生的有希望的治疗目标

Fabian Szepanowski, Mark Stettner

Implications of Olig2 silencing in oligodendrocyte precursor cells

Olig2 沉默在少突胶质细胞前体细胞中的意义

Li-Pao Fang, Xianshu Bai

The presence of functional blood vessels in the ischemic core provides a therapeutic target for stroke recovery

缺血核心中功能性血管的存在为脑卒中恢复提供了治疗靶点

Gary P. Morris, Brad A. Sutherland

Restoration of GABAB receptor expression in cerebral ischemia: a promising novel neuroprotective strategy

脑缺血时GABAB受体表达的恢复：一种有前途的新神经保护策略

Musadiq A. Bhat, Mohammad Hleihil, Dietmar Benke

Unexpected role of complement component 8 gamma chain in the inflamed brain

补体成分8伽马链在发炎的大脑中发挥了意想不到的作用

Jong-Heon Kim, Kyoungho Suk

‘Hippocampal innate inflammatory gliosis only’ – the future role of surgery in a novel temporal lobe epilepsy syndrome

“仅海马先天性炎症胶质增生”--手术在新型颞叶癫痫综合征中的未来作用

Alexander Grote, Daniel Delev

Advancing spinal cord injury research with optical clearing, light sheet microscopy, and artificial intelligence-based image analysis

用光学透明化、光片显微镜和基于人工智能的图像分析推进脊髓损伤研究

Qiang Li, Alfredo Sandoval Jr, Bo Chen

Trans-synaptic degeneration as a mechanism of neurodegeneration in multiple sclerosis

跨突触变性是多发性硬化神经变性的机制

Olwen C. Murphy, Peter A. Calabresi, Shiv Saidha

Recent advances in RNA-targeting therapy for neurological diseases

RNA靶向治疗神经系统疾病的研究进展

Satheesh Kumar, Guei-Sheung Liu

Axon guidance in regeneration of the mature central nervous system: step by step

成熟中枢神经系统再生中的轴突引导：循序渐进

Julia Schaeffer, Noemie Vilallongue, Stephane Belin, Homaira Nawabi

Calcium-permeable AMPA receptors: an underestimated pharmacological target for the therapy of brain pathologies

钙渗透性AMPA受体：一个被低估的治疗脑部病变的药理目标

Sergei G. Gaidin, Artem M. Kosenkov

CD74: a prospective marker for reactive microglia?

CD74：反应性小胶质细胞的潜在标志物？

Phani Sankar Potru, Björn Spittau

Exploration of C-terminal CX3CL1 for reducing age-dependent neurodegeneration

C末端CX3CL1减少年龄依赖性神经退行性变的探索

Jacob Hudobenko, Manoshi Gayen, Marc R. Benoit, Neeraj Singh, Riqiang Yan

Historic recurrences in medicinal chemistry: nature-inspired structures as a new opportunity for novel multi-target anti-Alzheimer’s drugs

药物化学的历史重现：受自然启发的结构是开发新型多靶点抗阿尔茨海默病药物的新机遇

Luca Piemontese

Cyclic adenosine monophosphate-elevating agents inhibit amyloid-beta internalization and neurotoxicity: their action in Alzheimer’s disease prevention

环磷酸腺苷提升剂抑制淀粉样蛋白β的内化和神经毒性：阿尔茨海默病预防中的作用

Rayudu Gopalakrishna, Andrew Oh, Narayan R. Bhat, William J. Mack

TREM2 as an evolving therapeutic target in Alzheimer’s disease

TREM2作为阿尔茨海默病的治疗靶点

Jacob George

Newfound physiological function of FAIM protein offers hope of novel disease-modifying therapy for Alzheimer’s disease

新发现的FAIM蛋白的生理功能为阿尔茨海默病的新型疾病治疗提供了希望

Allison R. Balaj, Hiroaki Kaku

Calcium handling: a strategy to fight neurodegeneration in Alzheimer’s disease

钙处理：对抗阿尔茨海默病神经退行性变的策略

Livia La Barbera, Elena Spoleti, Marcello D’Amelio

The tip of the iceberg? The underestimated potential of non-canonical beta-amyloids for Alzheimer’s disease

冰山一角被低估的非典型淀粉样蛋白β治疗阿尔茨海默病的潜力

Lukas Busch, Bernd Bufe

Implication of salivary lactoferrin and periodontal-mediated infections in Alzheimer’s disease

唾液乳铁蛋白和口腔感染在阿尔茨海默病中的意义

Cristina Municio, Eva Carro

OxInflammation in Alzheimer’s disease

阿尔茨海默病中的氧化应激炎症

Carlo Cervellati, Giovanni Zuliani, Giuseppe Valacchi

Cell replacement for Parkinson’s disease: advances and challenges

细胞替代治疗帕金森病：进展和挑战

Bin Xiao, Eng-King Tan

On the role of RNA binding proteins in polyglutamine diseases: from pathogenesis to therapeutics

RNA 结合蛋白在多聚谷氨酰胺疾病中的作用：从发病机制到治疗

André Conceição, Rebekah Koppenol, Clévio Nóbrega

Impaired lysosomes in the retinal pigment epithelium play a central role in the degeneration of the neuroretina

视网膜色素上皮中受损的溶酶体在神经视网膜退化中起着核心作用

Miller Rebecca, Ratnayaka J. Arjuna

Implication of gut microbiome in age-related macular degeneration

肠道微生物组在年龄相关性黄斑变性中的意义

Wendy Luo, Dimitra Skondra

The pathology behind glaucoma: what we already know using omics technologies

青光眼背后的病理学：利用组学技术已知的信息

Caroline May, Sabrina Reinehr

Is a mirror necessary for mirror therapy?

镜子对于镜像疗法是否必要？

Richard G. Carson, Alannah Morley

Meningeal T-cells in the cross-talk between memory consolidation and sleep

脑膜T细胞在记忆巩固和睡眠之间的串扰

Rodrigo Pacheco, Valentina Ugalde

Repurposing niclosamide for the treatment of neurological disorders

重新利用氯硝柳胺来治疗神经系统疾病

Savina Apolloni, Nadia D’Ambrosi

Etiology matters: genetic and acquired prion diseases engage different mechanisms at a presymptomatic stage

病因学问题：遗传性和获得性朊病毒疾病在症状前阶段具有不同的机制

Walker S. Jackson

研究原著

脑损伤与神经再生

Quantitative proteomic and phosphoproteomic analyses of the hippocampus reveal the involvement of NMDAR1 signaling in repetitive mild traumatic brain injury

海马体的定量蛋白质组学和磷酸化蛋白质组学分析揭示了 NMDAR1 信号在重复性轻度创伤性脑损伤中的作用

Zhicheng Tian, Zixuan Cao, Erwan Yang, Juan Li, Dan Liao, Fei Wang, Taozhi Wang, Zhuoyuan Zhang, Haofuzi Zhang, Xiaofan Jiang, Xin Li, Peng Luo

脊髓损伤与神经再生

Ca2+-induced myelin pathology precedes axonal spheroid formation and is mediated in part by store-operated Ca2+entry after spinal cord injury

脊髓损伤后Ca2+诱导的髓鞘病变先于轴突球状体形成的现象部分由库控钙内流介导

Spencer Ames, Kia Adams, Mariah E. Geisen, David P. Stirling

Fidgetin interacting with microtubule end binding protein EB3 affects axonal regrowth in spinal cord injury

Fidgetin通过与微管末端结合蛋白3相互作用影响脊髓损伤轴突的再生

Chao Ma, Junpei Wang, Qifeng Tu, Weijuan Bo, Zunlu Hu, Run Zhuo, Ronghua Wu, Zhangji Dong, Liang Qiang, Yan Liu, Mei Liu

Bexarotene improves motor function after spinal cord injury in mice

贝沙罗汀改善脊髓损伤后运动功能的机制

Xingyu Wang, Zhihao Shen, Haojie Zhang, Hao-Jie Zhang, Feida Li, Letian Yu, Hua Chen, Kailiang Zhou, Hui Xu, Sunren Sheng

Transcriptomic analysis of spinal cord regeneration after injury in Cynops orientalis

东方蝾螈脊髓损伤后神经再生的生物学和转录组分析

Di Wang, Man Zhao, Xiao Tang, Man Gao, Wenjing Liu, Minghui Xiang, Jian Ruan, Jie Chen, Bin Long, Jun Li

A novel mouse model of central cord syndrome

一种新型颈脊髓中央管综合征的模型

Elzat Elham – Yilizati Yilihamu, Xiangchuang Fan, Zimeng Yang, Shiqing Feng

周围神经损伤与神经再生

Motor neuron-specific RhoA knockout delays degeneration and promotes regeneration of dendrites in spinal ventral horn after brachial plexus injury

运动神经元特异性RhoA敲除可延缓臂丛神经损伤后脊髓腹角树突的退变并促进其再生

Mi Li, Jiawei Xu, Ying Zou, Jialing Lu, Aiyue Ou, Xinrui Ma, Jiaqi Zhang, Yizhou Xu, Lanya Fu, Jingmin Liu, Xianghai Wang, Libing Zhou, Jiasong Guo

Nerve function restoration following targeted muscle reinnervation after varying delayed periods

不同延迟时间靶向肌肉神经支配的神经功能重建

Yuanheng Li, Jiangping Huang, Yuling Chen, Shanshan Zhu, Zhen Huang, Lin Yang, Guanglin Li

神经退行性疾病与神经再生

Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways

生酮饮食改善APP/PS1小鼠的认知功能障碍和神经炎症

Jingwen Jiang, Hong Pan, Fanxia Shen, Yuyan Tan, Shengdi Chen

视神经损伤与神经再生

Selective deletion of zinc transporter 3 in amacrine cells promotes retinal ganglion cell survival and optic nerve regeneration after injury

无长突细胞选择性敲除锌转运蛋白3可促进视网膜神经节细胞存活和视神经再生

Zhe Liu, Jingfei Xue, Canying Liu, Jiahui Tang, Siting Wu, Jicheng Lin, Jiaxu Han, Qi Zhang, Caiqing Wu, Haishun Huang, Ling Zhao, Yehong Zhuo, Yiqing Li

病例报告

Acute penetrating injury of the spinal cord by a wooden spike with delayed surgery: a case report

木钉急性穿透性损伤脊髓的延迟手术干预：病例报告

James D. Guest, Zhuojing Luo, Yansheng Liu, Hongkun Gao, Dianchun Wang, Xiao-Ming Xu, Hui Zhu